The Best NAD+ Delivery Method: Buyer’s Guide

Step 1: Understand your options

• Oral NAD+ pills (NR/NMN): Easy to take, but limited by digestion. Variable NAD+ bioavailability.
• IV NAD+ drips: Highly effective, but require clinic visits and are costly.
• Subcutaneous NAD+ Pen: Bypasses digestion, offering high absorption and convenience from home.

Step 2: Prioritise bioavailability

If your body doesn’t absorb it, you won’t feel the benefits. Oral supplements may deliver under 20% to your system, while IV and subcutaneous methods support far higher availability.

Step 3: Consider lifestyle and cost

• Pills: Low effort, low cost, but weaker results.
• IV: Effective but expensive and time-consuming.
• NAD+ Pen: Effective, affordable, and time-efficient — ideal for busy professionals.

Step 4: Debunk common myths

• Myth: All NAD+ supplements work the same.
  Fact: Absorption depends on delivery method.
• Myth: Pills are enough for everyone.
  Fact: Many find minimal benefit due to low systemic absorption.
• Myth: IV is the only effective method.
  Fact: Subcutaneous delivery offers high efficacy without the hassle.

Step 5: Use this quick checklist

Ask yourself:

• Do I want a high-absorption NAD+ supplement that works reliably?
• Do I have time and budget for clinic visits, or do I prefer at-home use?
• Am I looking for a convenient, science-backed routine?

If you answered “yes” to the last two, the Holte NAD+ Pen is likely your best choice.

The most effective NAD+ supplement — combining high bioavailability with modern convenience.