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NAD+ Pen® Step-by-Step Guide

1. Prepare the Pen and Cartridge

  • Remove the Hōlte NAD+ Pen® and an NAD+ cartridge from their packaging.
  • Allow the NAD+ cartridge to rest at room temperature for 5–10 minutes.

2. Unscrew the Cartridge Holder

  • Take the lid off the pen to expose the clear cartridge holder.
  • Unscrew the clear cartridge holder from the base of the pen.
  • If the plunger is exposed, press it into the base of the pen with your finger.

3. Insert the NAD+ Cartridge

  • Take the NAD+ cartridge and insert it into the clear cartridge holder with the silver tip going in first.
  • Screw the clear cartridge holder (with the NAD+ cartridge inside) back onto the base of the pen firmly.

4. Prime the Pen

  • Twist the base of the pen until the dose meter is fully extended.
  • Push the dose meter back in and watch the plunger move up inside the cartridge holder.
  • Repeat this process until the plunger touches the bung at the bottom of the cartridge and you feel resistance.
  • Your pen is now prepped and ready for daily use. Continue with the steps below.