
NAD+ Pen® (Accessory)
A sleek, near-painless pen designed to deliver NAD+ with almost 100% bioavailability — supporting energy, clarity, and healthy aging. Includes fridge and travel case. NAD+ refill cartridges sold separately.
✔️ Recovery: Bounce back faster from workouts or fatigue
✔️ Focus: Enhance mental clarity and performance
✔️ Skin: Support healthy, glowing skin from within
✔️ Energy: Recharge your body

NAD+ Pen® (Accessory)
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NAD+ Pen™ + Travel Case
A sleek, near-painless pen designed to deliver NAD+ with almost 100% bioavailability — supporting energy, clarity, and healthy aging. Includes fridge and travel case. NAD+ refill cartridges sold separately.
Healthy aging from within.
The Hōlte NAD+ Pen™ is a simple, effective way to raise your NAD+ levels and support long-term health from within. With close to 100% bioavailability, our advanced delivery system ensures each dose is absorbed efficiently — helping to restore energy, improve mental clarity, elevate mood, and support cellular repair.
Designed for ease and comfort, the Pen offers a virtually painless, at-home wellness experience — no clinic visits or complex routines required.
This set includes:
- 1 x Hōlte NAD+ Pen™
- Fridge-safe case
- Travel case for easy portability
Note: This product includes the NAD+ Pen and travel case only. NAD+ refill cartridges are sold separately.
What’s Included
Hōlte NAD+ Pen™ - a sleek, reusable micro-needle device engineered for near-painless, high-absorption NAD+ delivery. Designed for convenience, comfort, and consistent performance — whether you're at home or on the go.
Fridge-safe storage case - protects your cartridges and helps maintain optimal temperature between uses.
Compact travel case - lightweight and discreet for easy use while travelling.
Note: Cartridges sold separately. The Hōlte Pen is also compatible with most standard NAD+ cartridges.
How To Use
How to Use Your Hōlte NAD+ Pen®
This guide provides step-by-step instructions to safely and effectively use your Hōlte NAD+ Pen® for subcutaneous injections. Please follow the steps carefully to ensure proper use.
1. Setting Up the Pen
- Prepare the Pen and Cartridge
Remove the Hōlte NAD+ Pen® and an NAD+ cartridge from their packaging. - Allow the NAD+ cartridge to rest at room temperature for 5–10 minutes.
2. Unscrew the Cartridge Holder
- Take the lid off the pen to expose the clear cartridge holder.
- Unscrew the clear cartridge holder from the base of the pen.
- If the plunger is exposed, press it into the base of the pen with your finger.
3. Insert the NAD+ Cartridge
- Take the NAD+ cartridge and insert it into the clear cartridge holder with the silver tip going in first.
- Screw the clear cartridge holder (with the NAD+ cartridge inside) back onto the base of the pen firmly.
4. Prime the Pen
- Twist the base of the pen until the dose meter is fully extended.
- Push the dose meter back in and watch the plunger move up inside the cartridge holder.
- Repeat this process until the plunger touches the bung at the bottom of the cartridge and you feel resistance.
- Your pen is now prepped and ready for daily use. Continue with the steps below.
Administering your NAD+ subcutaneous injection
1. Attach the needle
- Take a 4mm needle tip from the pack and gently but firmly screw it onto the end of the Hōlte NAD+ Pen®.
- Do not remove the needle tip cover yet
2 . Clean the injection site
- Use an alcohol wipe to clean the injection site.
- Choose a fatty area such as the abdomen (belly). Rotate the injection site each time to avoid skin damage or dimpling.
3. Set your dose
- Twist the base of the pen until the pointer lines up with your prescribed dose:
30 units (0.3ml) for a high dose.
15 units (0.15ml) for a maintenance dose. - Remove both the outer and inner needle tip covers.
4. Administer the Injection
- Gently pinch the skin around the injection site, pulling it about 4mm away from the muscle.
- Place the needle at the injection site and press the pen down to pierce the skin.
- Press the button at the base of the pen to depress the plunger and administer the NAD+.
- Hold the pen steady and count down three seconds before removing the needle.
5. Dispose of the Needle
- Carefully replace the outer needle tip cover.
- Unscrew the needle tip with the cover on and dispose of it in the sharps bin provided.
6. Store the Pen
- Replace the pen lid.
- Store the Hōlte NAD+ Pen® in the fridge (between 2–8°C / 35.6–46.4°F) to keep the NAD+ cartridge fresh.
Important Notes for Safe Use
- Rotate injection sites to prevent skin damage or dimpling.
- It is normal to experience the following after an injection:
- A drop of NAD+ or blood on the skin.
- A small bruise if the needle wasn't kept steady.
- A temporary red mark at the injection site. This will fade and is harmless.
If concerned about visible marks, consider injecting in areas covered by clothing. - Use a free needles for each use
- Use NAD+ cartridges before their expiration date.
- Keep cartridge refrigerated
Conformation of understanding
By using the Hōlte NAD+ Pen®, you confirm the following:
- You will administer NAD+ subcutaneously only, as instructed.
- You understand the risks (e.g., allergic reaction, infection) and commit to following the instructions exactly.
- You are competent to perform subcutaneous injections and will dispose of needles appropriately.
- Hōlte is not responsible for any adverse effects caused by improper use or failure to follow the instructions.
Important: This product is not intended to diagnose, treat, or cure any condition. Always consult a healthcare professional before starting NAD+ injections. Use sterile technique to avoid contamination or infection.
Benefits of NAD+
NAD+ is a naturally occurring molecule that plays a vital role in supporting key cellular processes. While maintaining healthy NAD+ levels is linked to overall wellness, our NAD+ Pen™ is designed to encourage and support a healthy, balanced lifestyle.
• Supports Energy Production: NAD+ is central to cellular energy processes, helping your body function at its best.
• Encourages Cellular Maintenance: A key component in supporting natural cellular repair mechanisms.
• Promotes Wellness: Plays a vital role in maintaining a healthy metabolic balance.
• Supports Healthy Aging: A fundamental molecule involved in cellular health as part of a balanced lifestyle.
Please note: These statements have not been evaluated by the Food Standards Agency. This product is not intended to diagnose, cure, manage, prevent, or treat any disease or condition.
Shipping & Returns
We ship all Holte NAD+ Pens and refills chilled with DPD Next Day to keep them in perfect condition.
- Orders placed today are dispatched the next working day.
- Delivery arrives the day after dispatch.
- You’ll receive tracking details once your order is on its way.
Cost
Free UK shipping on orders over £100
£8 delivery for UK orders under £100